ABSTRACT
BACKGROUND: The COVID-19 pandemic, which started in December 2019, is still continuing to date (November 2021), and nobody knows how long it will remain. During this time, the world remains vigilant against the pandemic, causing new problems in various fields of life. At the same time, the public continues getting latest information about COVID-19. One and a half year is not a short time to continuously carry out COVID-19 preventive behavior, which in turn causes relaxation of COVID-19 preventive behavior. AIM: This study aims to determine the correlation between knowledge and COVID-19 preventive behavior after 1 year of pandemic among medical students and to find out factors that affect knowledge about COVID-19. METHOD(S): This is a descriptive-analytic cross-sectional study with 261 respondents collected from students of the Faculty of Medicine, Universitas Sumatera Utara. Respondents' data were collected using an online questionnaire which had been tested for its validity and reliability. Distribution of sample size used proportionate stratified random sampling and simple random sampling. Data will be analyzed using Chi-square. RESULT(S): Of the 261 respondents analyzed, 247 respondents (94.7%) had good level of knowledge, 222 respondents (85.1%) had good level of preventive behavior, and the factors that influenced knowledge were the year of admission (p = 0.028) and family member with past confirmed case of COVID-19 (p = 0.011). The knowledge and preventive behavior relationship analysis showed p = 0.009 (PR = 4.864 [95% CI: 1.587-14.909]). CONCLUSION(S): Even though the pandemic has lasted for more than 1 year, medical students with good level of knowledge still carry out good preventive behavior showing a meaningful relationship between knowledge and preventive behavior. Level of knowledge is influenced by the year of admission and family member with past confirmed case of the year of admission and family member with past confirmed case of COVID-19.Copyright © 2023 Chandra Pranata Salim.
ABSTRACT
Background: Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). The increase in the number of COVID-19 cases was happening quite quickly and has spread between countries so that COVID-19 has become a pandemic in the world. This study aimed to determine the characteristics of COVID-19 patients at Haji Adam Malik General Hospital Medan. Method: This was a descriptive study. Data were taken from the medical records of 110 hospitalized patients with positive RT-PCR results for COVID-19 from December 2020 to April 2021. The inclusion criteria for the case samples were patients diagnosed with COVID-19 based on RT-PCR and the exclusion criteria were incomplete medical records. Characteristic analysis was carried out using the Kruskal Wallis test.
ABSTRACT
BACKGROUND: Pregnancy state affects the immune regulation including physical barrier, innate, and adaptive immunity-related to susceptibility of infections and increasing risk for severe to critical case of COVID-19. Further, high risk of thrombosis becomes a challenge in the management of COVID19 in pregnancy due to the strong association with worse outcome. CASE REPORT: Here, we present three cases of pregnant women infected with COVID-19 pneumonia with different outcomes in maternal and fetal condition related to high-risk thrombosis. Serial inflammatory markers were needed to the early detect the disease progressivity in pregnant women with COVID-19. Further, complete assessment of fetus including reverse transcriptase-polymerase chain reaction and chest X-ray must be performed to the early diagnosis of COVID-19 in neonatal whose mother was infected by SARS-CoV-2. CONCLUSION: Pregnancy state affects the immune regulation including physical barrier, innate, and adaptive immunity-related to susceptibility of infections and increasing risk for severe to critical case of COVID-19. Further, high risk of thrombosis becomes a challenge in the management of COVID19 in pregnancy due to the strong association with worse outcome. Although fetal transmission of COVID-19 to fetus remains unclear, complete assessment of fetus including RT-PCR, and chest X-ray must be performed to the early diagnosis of COVID-19 in neonatal whose mother was infected by SARS-CoV-2.
ABSTRACT
BACKGROUND: Coronavirus disease 2019 (COVID-19) has distracted the global health system due to significant morbidity and mortality. There are increasing mortality rates related to the existence of comorbidities. Due to immunologic conditions, other infectious diseases, such as multidrug-resistant tuberculosis (MDR-TB), might coinfect with COVID-19. We describe a case of MDR-TB with diabetes mellitus and critical COVID-19 patient with fatal outcome. CASE REPORT: A 60-year-old man was admitted to our hospital with shortness of breath for 2 days. A history of recurrent shortness of breath has had developed for about 7 months. Room air oxygen saturation was at 66%. RT-PCR SARS-CoV-2 nasopharynx swab result was positive. The chest X-ray series result showed destroyed left lung with increasing infiltrate in the lower right lung. The patient was diagnosed with pulmonary MDR-TB based on GeneXpert and LPA (Line Probe Assay) test 6 months prior and also has had history of diabetes mellitus for 7 years. Then, the patient was diagnosed with COVID-19, pulmonary MDR-TB, and diabetes mellitus. MDR-TB regimen, anti-diabetic medication, and management of COVID-19 were carried out. On the 6th day, the patient’s condition worsened to the point, where he needed intubation. The patient eventually passed away. CONCLUSION: The treatment outcome was highly related to the severity of COVID-19 symptoms and complications of comorbidities when patients are admitted to the hospital. The early screening and treatment of COVID-19 are important to prevent deteriorating clinical conditions caused by comorbidities.
ABSTRACT
BACKGROUND: The pandemic that occurred at the end of 2019 was caused by the coronavirus 2 (Severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]). Various speculations mention that the long-term effects of coronavirus disease 2019 (COVID-19) infection can cause pulmonary fibrosis. Acute respiratory distress syndrome (ARDS) is one that can cause pulmonary fibrosis due to injury to the lungs. CASE REPORT: This report discusses a case of pulmonary fibrosis caused by critical COVID-19 (Coronavirus disease) in 38-year-old male patient with hypertension and obesity comorbidities. The patient was treated for 51 days in intensive care unit with 60 L/min high flow nasal cannula assisted oxygenation;then his condition improved as evidenced by his negative Real Time-Polymerase Chain Reaction test result, and was subsequently transferred to a non-COVID-19 ward using non-rebreathing mask at 10–15 L/min, which was later titrated to 2–4 L/min nasal canulla. Patient was treated in the non-COVID ward for 16 days. The total number of days of hospitalization was 67 days. Patient had his thorax photo taken 3 times and non-contrast thorax computed tomography (CT) scan 3 times. Based on the evaluation of his thorax CT scan on day 23, we found a vast fibrosis in patient’s lungs. Many literatures state that lung fibrosis can be triggered by ARDS, a condition due to the infection from SARS-CoV-2. CONCLUSION: COVID-19 infection can progress overtime and may cause pulmonary fibrosis. The most serious phase of this virus infection is characterized by sudden and excessive release of proinflammatory mediators that lead to lung damage with large fibrosis and rapid onset of ARDS. To further our understanding of this issue, we present the case report of lung fibrosis caused by critical COVID-19 infection.